山東大學生命科學學院導師：夏光敏 正文

　　夏光敏 教授
　　博士生導師
　　生命科學學院黨委書記兼副院長
　　0531-88364525 13082745752
　　xiagm@sdu.edu.cn
　　
　　教育背景
　　1987年山東大學研究生畢業留校工作至今 1996年澳大利CSIRO植物分子生物學實驗室訪問學者 2001年英國John Innes Centre訪問學者。
　　現任教育部生物技術學科教學指導委員會委員，山東省植物生理學會副理事長，中國植物生理學會理事及植物生物技術專業委員會主任，中國農業生化與分子生物學學會理事，中國細胞生物學會會員，中國遺傳學會會員，國際組織培養與生物技術學會會員。
　　
　　研究方向
　　細胞生物學專業,植物細胞與基因工程方向;以及遺傳學專業,植物細胞與分子遺傳方向。主要從事小麥及草類的細胞工程和基因工程育種及相關的基礎理論研究。在國際上首次建立了小麥體細胞雜交創制漸滲系育種新技術, 利用此技術創制了一批各具特色的育種新種質;利用這些新材料，進行了體細胞雜種漸滲系的發育、遺傳、外源基因漸滲、基因突變、基因表達變異和表觀遺傳學變化以及耐逆和優質的功能基因研究;承擔研究生的植物功能基因組專題及生命科學前沿進展等課程。
　　
　　主講課程：
　　植物功能基因組專題及生命科學前沿進展
　　培養研究生：（含聯合培養研究生）
　　已經培養博士研究生20多人，再讀博士研究生10余人。
　　與美國Oklahoma大學、美國農業部USDA-ARS，美國The Samuel Roberts Noble Foundation，及澳大利亞Adelaide大學等聯合培養博士生6人。
　　
　　本人研究生從事的工作領域：
　　作物遺傳育種，作物功能新基因的分離與功能鑒定，植物細胞工程與育種，植物基因工程與育種，作物分子生物學研究
　　
　　承擔課題
　　目前主持國家轉基因專項，國家自然科學基金重點和面上項目、國家863項目，參加國家973項目，國家支撐計劃等。
　　1.抗旱、耐鹽轉基因小麥新種質創建，國家轉基因專項，2008-2010，300萬
　　2.小麥漸滲系耐鹽新基因的鑒定，國家轉基因專項, 2009-2010，350萬
　　3.小麥體細胞雜交新品種耐鹽的功能基因研究，2005-2009，國家自然科學基金重點項目，150萬
　　4.耐逆性狀分子設計和育種元件創新，國家973，2006-2010，58萬
　　5.作物應答低溫、高鹽的分子機制，國家973，2009-2014，52萬
　　6.小麥體細胞雜種漸滲系HMW-GS基因的等位變異，國家自然科學基金項目，2009-2011，33萬
　　
　　研究成果及發表論文
　　長期從事小麥及草類的細胞有基因工程研究，為小麥體細胞雜交技術及其機制，雜種新種質、新品種的首創者，該技術2007年獲得國家發明專利（ZL200410075773.2）。選育了國際首例高產、耐鹽/耐旱的小麥漸滲系新品種山融3號（該品種被定為2006年山東省良種主導品種）。小麥體細胞雜交技術2005年通過董玉琛院士等國內同行專家的鑒定，“是小麥生物技術育種技術上一項重要突破，總體研究達到國際領先水平。以上研究在國際、全國會議上作大會報告10次，“小麥不對稱體細胞雜交機制及雜種遺傳和基因組研究” 獲2006年山東省唯一的自然科學一等獎(第一位）。在國內首次建立了小麥的基因槍轉化和農桿菌介導轉化技術，與中國農科院合作的“大麥BYDV轉化小麥（完成基因槍轉化小麥部分）獲得抗病新種質”被科技部評選為1995年全國十大科技成就。在國內率先建立了利用該技術轉化小麥胚性愈傷組織的體系， 經過近6年的研究, 又建立了農桿菌介導小麥苗端轉化體系,該項新技術2006年獲得國家發明專利（ZL200410075774.7）. 目前已經獲得大量轉入抗病、耐鹽、優質等轉基因的后代，并且獲批環境釋放，為小麥的基因工程育種奠定了基礎。作為第一作者和通訊作者發表在本領域主流SCI源刊物上50余篇，總IF 100 以上，被引用250多次，其中3篇文章分別被他引35，40，40和次以上，兩篇為雜志的2003-2008的TOP 3和TOP 10；受邀參編國際專著3部。
　　
　　獲獎項目：
　　“小麥不對稱體細胞雜種的遺傳和基因組研究”2006年山東省自然科學一等獎（第一位）“小麥不對稱體細胞雜交創制漸滲系新技術”，2008年教育部技術發明二等獎（第一位）
　　
　　發表的SCI論文：(*通訊作者)
　　1. Peng, Z.Y., Wang, M.C., Li, C.L., Li, F., Liu, C., and Xia, G.M. 2009， A proteomic study of the response to salinity and drought stress in an introgression strain of bread wheat. Molecular & Cellular Proteomics, 10.1074mcp.M900052-MCP200 IF=8.834
　　2. Chen FG, Liu S, Zhao F, Xu C, Xia G. 2009, Molecular characterization of the low-molecular weight glutenin subunit genes of tall wheatgrass and functional properties of one clone Ee34. Amino Acids, DOI: 10.1007/s00726-009-0307-y IF=4.132
　　3. Liu H, Liu S, Xia G. Generation of high frequency of novel alleles of the high molecular weight glutenin in somatic hybridization between bread wheat and tall wheatgrass. 2009, Theor. Appl. Genet. 118(6):1193-1198. IF=3.490
　　4. Cui H, Yu Z, Deng J, Gao X, Sun Y, Xia G. 2009, Introgression of bread wheat chromatin into tall wheatgrass via somatic hybridization. Planta. 229(2):323-330，IF=3.088
　　5. Chen FG, Zhao F, Liu S, Xia G*. 2009, The γ-gliadin gene content of a derivative from a somatic introgression line II-12 derived from Triticum aestivum and Agropyron elongatum. Mol Breeding, DOI: 10.1007/s11032-009-9275-x. IF=2.008
　　6. Han L, Zhou C, Shi J, Zhi D, Xia G. 2009, Ginsenoside Rb1 in asymmetric somatic hybrid calli of Daucus carota with Panax quinquefolius. Plant Cell Reports. 28(4):627-638.IF=1.946
　　7. Guangmin Xia* 2009，Progress of chromosome engineering mediated by asymmetric somatic hybridization. Journal of Geneticsand Genomics, 36(9):547-556(特邀綜述). IF=0.358
　　8. Shan, L., Li, C.L., Chen, F., Zhao, S.Y., and Xia, G.M. 2008. A Bowman-Birk type protease inhibitor is involved in the tolerance to salt stress in wheat. Plant Cell Environ. 31, 1128 - 1137. IF=4.666
　　9. Wang, M.C., Peng, Z.Y., Li, C.L., Li, F., Liu, C., and Xia, G.M. 2008. Proteomic analysis on a high salt tolerance introgression strain of Triticum aestivum/Thinopyrum ponticum. Proteomics 8, 1470 - 1489. IF=4.586
　　10. Liu, S.W., Gao, X., and Xia, G.M. 2008. Characterizing HMW-GS alleles of decaploid Agropyron elongatum in relation to evolution and wheat breeding. Theor. Appl. Genet. 116, 325-334. IF=3.490
　　11. Chen, F.G., Xu, C.H., Chen, M.Z., Wang, Y.H., and Xia, G.M. 2008. A new α-gliadin gene family for wheat breeding: somatic introgression line II-12 derived from Triticum aestivum and Agropyron elongatum. Mol. Breeding, 2008, 22(4): 675-685. IF=2.008
　　12. Liu, S.W., Gao, X., Lu, B.R., and Xia, G.M. 2008. Characterization of the genes coding for the high molecular weight glutenin subunits in Lophopyrum elongatum. Hereditas 145, 48-57. IF=1.175
　　13. Wang, M.Q., Zhao, J.S., Peng, Z.Y., Guo, W., Wang, Y., Wang, L., and Xia, G.M. 2008. Chromosomes are eliminated in the symmetric fusion between Arabidopsis thaliana L. and Bupleurum scorzonerifolium Willd. Plant Cell Tiss Organ Cult 92, 121-130. IF=1.017
　　14. Liu, S.W., Zhao, S.Y., Chen, F.G., and Xia, G.M. 2007. Generation of novel high quality HMW-GS genes in two introgression lines of Triticum aestivum/Agropyron elongatum. BMC Evol. Biol. 7, 76-83. IF=4.46
　　15. Chen, F.G., Luo, Z., Zhang, Z.G., Xia, G.M., and Min, H.X. 2007. Variation and potential value in wheat breeding of low-molecular-weight glutenin subunit genes cloned by genomic and RT-PCR in a derivative of somatic introgression between common wheat and Agropyron elongatum. Mol. Breeding 20, 141-152. IF=2.357
　　16. Zhao, J.S., Zhi, D.Y., Xue, Z.Y., Liu, H., and Xia, G.M. 2007. Enhanced salt tolerance of transgenic progeny of tall fescue (Festuca arundinacea) expressing a vacuolar Na+/H+ antiporter gene from Arabidopsis. J. plant Physiol. 164, 1377-1383. IF=1.403
　　17. Cai, Y.F., Xiang, F.N., Zhi, D.Y., Liu, H., and Xia, G.M. 2007. Genotyping of somatic hybrids between Festuca arundinacea Schreb. and Triticum aestivum L. Plant Cell Rep. 26, 1809-1819. IF=2.173
　　18. Deng, J.Y., Cui, H.F., Zhi, D.Y., Zhou, C.E., and Xia, G.M. 2007. Analysis of remote asymmetric somatic hybrids between common wheat and Arabidopsis thaliana. Plant Cell Rep., 1233-1241. IF=2.173
　　19. Zhao, J.S., Ren, W., Zhi, D.Y., Wang, L., and Xia, G.M. 2007. Arabidopsis DREB1A/CBF3 bestowed transgenic tall fescue increased tolerance to drought stress. Plant Cell Rep 26, 1521-1528. IF=2.173
　　20. Zhou, C.E., Xia, G.M., Zhi, D.Y., and Chen, Y. 2006. Genetic characterization of asymmetric somatic hybrids between Bupleurum scorzonerifolium Willd and Triticum aestivum L.: potential application to the study of the wheat genome. Planta 223, 714-724. IF=3.238
　　21. Liu, H., Shi, L., Zhao, J.S., and Xia, G.M. 2006. Genetic characteristic of HMW-GS in somatic hybrid wheat lines - potential application to wheat breeding. J. Agric. Food Chem. 54, 5007 -5013. IF=2.532
　　22. Zhao, T.J., Zhao, S.Y., Chen, H.M., Zhao, Q.Z., Hu, Z.M., Hou, B.K., and Xia, G.M. 2006. Transgenic wheat progeny resistant to powdery mildew generated by Agrobacterium inoculum to the basal portion of wheat seedling. Plant Cell Rep. 25, 1199-1204. IF=1.727
　　23. Chen, F.-G., Zhi, D.-Y., and Xia, G.-M. 2005. Wheat amino acid analysis in single cells by intracellular FITC- derivatization with PEG. Electrophoresis 26, 4204-4205. IF=4.04
　　24. Luo, Z., Chen, F.G., Feng, D.S., and Xia, G.M. 2005. LMW-GS genes in Agropyron elongatum and their potential value in wheat breeding. Theor. Appl. Genet. 111, 272-280. IF=3.063
　　25. Wang, J., Xiang, F.N., and Xia, G.M. 2005. Agropyron elongatum chromatin localization on the wheat chromosomes in an introgression line. Planta 221, 277-286. IF=2.963
　　26. Chen, F.-G., Zhi, D.-Y., and Xia, G.-M. 2005. Analysis of amino acids in individual wheat embryonic protoplast. Amino acids 29, 235-239. IF=2.78

　　27. Cheng, A.X., Cui, H.F., and Xia, G.M. 2006. Construction of a primary RH panel of Italian ryegrass genome via UV-induced protoplast fusion. Plant Bio. 8, 673-679. IF=1.910
　　28. Zhou, A.F., and Xia, G.M. 2005. Introgression of the Haynaldia villosa genome to γ-ray induced asymmetric somatic hybrids of wheat. Plant Cell Rep. 24, 289-296. IF=1.727
　　29. Wang, M.Q., Xia, G.M., and Peng, Z.Y. 2005. High UV-tolerance with introgression hybrid formation of Bupleurum scorzonerifolium Will. Plant Sci. 168, 593-600. IF=1.621
　　30. Shan, L., Zhao, S.Y., and Xia, G.M. 2005. Cloning of the full-length cDNA of the wheat involved in salt stress--root hair defective 3 gene (RHD3). J. Integr. Plant Biol. 47, 885-891 IF=0.515
　　31. Chen, S.Y., Liu, S.W., Xu, C.H., Chen, Y.Z., and Xia, G.M. 2004. Heredity of chloroplast and nuclear genomes of asymmetric somatic hybrid lines between wheat and couch grass. ACTA Botan. Sin. 46, 110-115. IF=0.321
　　32. Chen, S.Y., Xia, G.M., Quan, T.Y., and Xiang, F.N. 2004. Studies on the salt-tolerance of F3-F6 hybrid Lines originated from somatic hybridization between common wheat and Thinopyrum ponticum. Plant Sci. 167, 773-779.IF=1.631
　　33. Cheng, A.X., and Xia, G.M. 2004. Somatic hybridization between common wheat and Italian ryegrass. Plant Sci. 166, 1219-1226. IF=1.631
　　34. Cheng, A.X., Xia, G.M., and Chen, H.M. 2004. DNA transfer from wild millet to common wheat by asymmetric somatic hybridization. ACTA Botan. Sin. 46, 1114-1121. IF=0.321
　　35. Cheng, A.X., Xia, G.M., Zhi, D.Y., and Chen, H.M. 2004. Intermediate fertile Triticum aestivum (+) Agropyron elongatum somatic hybrids are generated by low doses of UV irradiation. Cell Research 14, 86-91.IF=2.161
　　36. Feng, D.S., Chen, F.G., Zhao, S.Y., and Xia, G.M. 2004. Study on coding genes of high-molecular-weight glutenin subunits in decaploid Agropyron elongatum (Host) Neveski. ACTA Botan. Sin. 46, 489-496. IF=0.321
　　37. Feng, D.S., Xia, G.M., Zhao, S.Y., and Chen, F.G. 2004. Two quality-associated HMW glutenin subunits in a somatic hybrid line between Triticum aestivum and Agropyron elongatum. Theor Appl Genet 110, 136-144. IF=3.063
　　38. Li, C.L., Xia, G.M., Xiang, F.N., Zhou, C.E., and Cheng, A.X. 2004. Regeneration of asymmetric somatic hybrid plants from the fusion of two types of wheat with Russian wildrye. Plant Cell Rep. 23, 461-467.IF=1.42
　　39. Wang, J., Xiang, F.N., and Xia, G.M. 2004. Transfer of small chromosome fragments of Agropyron elongatum to wheat chromosome via asymmetric somatic hybridization. Sci. China Ser. C 47, 434-441.IF=0.482
　　40. Xiang, F.N., Xia, G.M., Zhi, D.Y., Wang, J., Hu, N., and Chen, H.M. 2004. Hybrid plant regeneration in relation to the nuclear and cytoplasmic genomes of wheat and Setaria italica. Genome 47, 680-688. IF=2.07
　　41. Xue, Z.-Y., Zhi, D.-Y., Xue, G.-P., Zhang, H., Zhao, Y.-X., and Gang-Min Xia*, 2004. Enhanced salt tolerance of transgenic wheat (Tritivum aestivum L.) expressing a vacuolar Na+/H+ antiporter gene with improved grain yields in saline soils in the field and a reduced level of leaf Na+. Plant Sci 167, 859-899.IF=1.605
　　42. Xia, G.M., Xiang, F.N., Zhou, A.F., Wang, H., and Chen, H.M. 2003. Asymmetric somatic hybridization between wheat (Triticum aestivum L.) and Agropyron elongatum (Host) Nevishi. Theor. Appl. Genet. 107, 299-305. IF=2.981
　　43. Xiang, F.N., Xia, G.M., and Chen, H.M. 2003. Effect of UV dosage on somatic hybridization between common wheat (Triticum aestivum L.) and Avena sativa L. Plant Sci. 164, 697-707. IF=1.389
　　44. Xiang, F.N., Xia, G.M., and Chen, H.M. 2003. Asymmetric somatic hybridization between wheat (Triticum aestivum) and Avena sativa L. Sci. China Ser. C, 243-252. IF=0.481
　　45. Xu, C.H., Xia, G.M., Zhi, D.Y., Xiang, F.N., and Chen, H.M. 2003. Integration of maize nuclear and mitochondrial DNA into the wheat genome through somatic hybridization. Plant Sci. 165, 1001-1008. IF=1.389
　　46. Zhou, A.F., Xia, G.M., Chen, X.L., and Chen, H.M. 2002. Produciton of somatic hybrid plants between two types of wheat protoplasts and the protoplasts of Haynaldia villosa. Acta Botan. Sin. 44, 1004-1008.
　　47. Yue, W., and Xia, G.M. 2001. Transfer of salt tolerance from Aeleuropus littoralis sinensis to wheat (Triticum aestivum L.) via asymmetric somatic hybridization. Plant Sci. 161, 256-262.
　　48. Zhou, A.F., Xia, G.M., and Chen, H.M. 2001. Comparative study of symmetric and asymmetric somatic hybridization between common wheat and Haynaldia villosa. Sci. China Ser. C, 294-304.
　　49. Zhou, A.F., Xia, G.M., Zhang, X., Chen, H.M., and Hu, H. 2001. Analysis of chromosomal and organellar DNA of somatic hybrids between Triticum aestiuvm and Haynaldia villosa Schur. Mol. Genet. Gen. 265, 387-393.
　　50. Xia, G.M., Li, Z.Y., Wang, S.L., Xiang, F.N., Chen, P.D., and Liu, D.J. 1998. Asymmetric somatic hybridization between haploid common wheat and UV irradiated Haynaldia villosa. Plant Sci. 137, 217-223.
　　51. Xia, G.M., and Chen, H.M. 1996. Plant regeneration from intergeneric somatic hybridization between Trticum aestivum L and Leymus chinensis (Trin) Tzvel. Plant Sci. 120, 197-203.
　　52. Xia, G.M., Wang, H., and Chen, H.M. 1996. Plant regeneration from intergeneric asymmetric somatic hybridization between wheat (Triticumn aestivum L.) and Russian wildrye (Psathyrostachys juncea (Fisch) Neweski) and couch grass (Agropyron elongatumn Host Neviski). Chin. Sci. Bull. 41, 1382-1386.
　　53. Zhou, A.F., Xia, G.M., and Chen, H.M. 1996. Asymmetric somatic hybridization between Triticum aestivum and Haynaldia villosa Schur. Sci. China Ser. C 39, 617-626.
　　54. Guo, G.Q., Xia, G.M., and Li, Z.Y. 1990. Direct somatic embryogenesis and plant-regeneration from protoplast-derived cells of wheat (triticum aestivum). Sci China Ser. B 34, 438-445.
　　合作發表的SCI論文：
　　55. Xianzhong Huang1,6, Qian Qian2,6, Zhengbin Liu1, Hongying Sun1, Shuyuan He1, Da Luo3, Guangmin Xia4, Chengcai Chu5, Jiayang Li5 & Xiangdong Fu1，2009 NATURE GENETICS，41：494-497，IF=30.259
　　56. Bottley, A., Xia, G.M., and Koebner, R.M.D. 2006. Homoeologous gene silencing in hexaploid wheat. Plant J. 47, 897-906. IF=6. 565

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